Daniel Reich, M.D., Ph.D.

Senior Investigator, NINDS
Translational Neuroradiology Section

Dr. Daniel Reich is Senior Investigator at NIH/NINDS, where he directs the Translational Neuroradiology Section and leads clinical studies focusing mainly on multiple sclerosis (MS). He is also an attending neuroradiologist at the NIH Clinical Center and an Adjunct Professor of Radiology, Neurology, and Biostatistics at Johns Hopkins University.

Dr. Reich studied math and physics at Yale and earned his M.D. from Cornell and his Ph.D. in neurophysiology from The Rockefeller University, where he studied how nerve cells in the visual system encode what we see. His further training includes a fellowship in diagnostic neuroradiology and residencies in radiology and neurology at Johns Hopkins Hospital.

Dr. Reich is a founder of the North American Imaging in MS (NAIMS) Cooperative. He serves on the Board of Directors of the Americas Committee for Treatment and Research in MS, the International Advisory Committee on Clinical Trials in Multiple Sclerosis, the Board of Professors of the Tuscan PhD Program in Neurosciences at the Universities of Florence, Pisa, and Siena, the Scientific Advisory Board of the Canadian Progressive Multiple Sclerosis Cohort, and the Editorial Board of Multiple Sclerosis Journal. He is also federal liaison to the International Biomedical Research Alliance. Dr. Reich is an elected member of the Association of American Physicians, the American Society of Clinical Investigation, and the Henry Kunkel Society, and he has won the American Neurological Association’s Derek Denny-Brown Young Neurological Scholar Award, the National MS Society’s Barancik Award for Innovation in MS Research, and the NIH Graduate Partnership Programs Outstanding Mentor Award.

Research in Dr. Reich’s NIH lab develops advanced MRI techniques to understand MS and adapts those techniques for clinical trials and patient care. The lab conducts investigator-initiated interventional clinical trials and harnesses noninvasive imaging modalities to dissect biological mechanisms of tissue damage, both by performing longitudinal studies on time scales relevant for disease processes and by examining radiological-pathological correlations in autopsy tissue and animal models. Dr. Reich has authored around 250 peer-reviewed publications, presented around 150 invited lectures across the world, and has been principal or associate investigator of more than 50 clinical protocols. In 2018, Dr. Reich’s lab discovered that human and nonhuman primates have a lymphatic system in the membranes covering the brain and showed how that system can be imaged noninvasively with MRI.